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how many acetaminophen can i take at once

For most healthy adults, the usual maximum is no more than 1,000 mg (1 gram) of acetaminophen at one time , and no more than 4,000 mg total in 24 hours from all sources (including cold/flu meds).

However, the safe amount for you personally can be lower and depends on your body weight, liver health, alcohol use, age, and other medicines you take. Because overdose can cause serious and sometimes fatal liver damage, you should never exceed the label dose, never “stack” different products that contain acetaminophen, and call a doctor, local poison center, or emergency services immediately if you may have taken too much or are thinking about taking a large amount on purpose.

If you tell me:

  • Your age
  • Approximate weight
  • The exact product strength (e.g., 325 mg, 500 mg)
  • Any liver problems or regular alcohol use

I can help you interpret the usual dosing limits in a more tailored way (not a substitute for urgent medical care).