US Trends

what weapon poisons do assasination rogues use

Assassination rogues typically use Deadly Poison and Instant Poison on their weapons in PvE. A common setup is to put Deadly Poison on the faster dagger and Instant Poison on the other weapon, with the exact main-hand/off- hand choice depending on the fight length and your gear.

Usual poison setup

  • Deadly Poison on the fast weapon, because faster swings help it stack and apply more often.
  • Instant Poison on the other weapon, since it benefits from weapon hit frequency and adds extra damage on procs.

Practical rule

  • For longer boss fights, many guides favor keeping Deadly Poison on the main hand and Instant Poison on the off-hand, or swapping based on which dagger is strongest.
  • For short fights or trash, some players prefer Instant Poison in the main hand for immediate damage.

Simple takeaway

If you want the standard answer: use Deadly Poison + Instant Poison. The fastest weapon usually gets Deadly Poison, and the higher-damage weapon often gets Instant Poison.