when do they break out of prison on prison break

They break out of Fox River prison at the very end of season 1, starting in episode 21 and completing it in episode 22.

When the escape happens

• The actual escape operation begins in season 1, episode 21, titled “Go” , when Michael and the team finally put the tunnel plan into action.

• The escape continues and concludes in season 1, episode 22, “Flight” , where the Fox River Eight make it over the wall and go on the run.

In‑universe timing

• A fan‑compiled timeline places Michael’s time in Fox River at roughly a month and a half, with the breakout occurring in late May 2005 within the story’s timeline.

• So in terms of watching order: finish season 1 to see the prison break itself; season 2 then follows the aftermath of that escape.

TL;DR: If you’re just wondering “when do they break out of prison on Prison Break?” — it happens at the end of season 1, across episodes 21 and 22.

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