where does dna replication take place in the cell

DNA replication takes place where the DNA is located: in the nucleus of eukaryotic cells and in the nucleoid region of prokaryotic cells. In eukaryotes, this happens during the S phase of the cell cycle before the cell divides.

Main locations in the cell

• In eukaryotic cells (like plant and animal cells), DNA is housed in the nucleus, so replication occurs inside the nucleus.

• In prokaryotic cells (like bacteria), there is no membrane-bound nucleus, so replication occurs in the nucleoid region of the cytoplasm where the chromosome sits.

Extra detail (helpful for class)

• Replication starts at specific DNA sites called origins of replication , where the double helix first unwinds.

• It takes place during the S (synthesis) phase of interphase, so each daughter cell gets a complete copy of the genome at division.

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