which two molecules make up the backbone of dna?

The backbone of a DNA molecule is made of two alternating molecules: a deoxyribose sugar and a phosphate group.

Quick Scoop

• DNA is often compared to a twisted ladder, and the sides of that ladder are formed by repeating units of sugar (deoxyribose) and phosphate.

• These sugar and phosphate groups link together to form a strong, stable chain called the sugar‑phosphate backbone.

• The nitrogenous bases (A, T, C, G) attach to the sugar part of this backbone and pair in the center, forming the “rungs” of the ladder.

So, when asked “which two molecules make up the backbone of DNA?”, the answer is: deoxyribose sugar and phosphate groups.

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