Cats do get a euphoric "high" from catnip, triggered by its active compound nepetalactone, which binds to receptors in their nasal tissue and stimulates endorphin release.

How Catnip Works

Nepetalactone in catnip enters through the cat's vomeronasal organ (in the roof of their mouth), mimicking an opioid-like effect on the brain's olfactory bulb, amygdala, and hypothalamus. This leads to a burst of feel-good endorphins, causing behaviors like rolling, rubbing, purring, drooling, and playful zooming—lasting about 5-15 minutes before a calm phase kicks in for up to an hour. Not all cats respond; only about 70-80% carry the sensitive gene, and kittens under 3 months or seniors often ignore it.

Common Reactions

  • Euphoric frenzy : Cats flip, kick, and chase imaginary foes in blissed-out abandon.
  • Chill aftermath : Post-high, they nap contentedly, fully relaxed.
  • Varied intensity : Some go wild; others just sniff politely—no two cats react identically.

Imagine your tabby suddenly channeling a tiny rockstar, thrashing on the carpet like it's discovered feline nirvana—pure, harmless fun rooted in their opioid system.

Safety and Limits

Cats can't overdose fatally or get addicted, as endorphins self-regulate without withdrawal, though tolerance builds with daily use. Excess might cause mild vomiting or diarrhea, so limit to every 2-3 weeks; start small to gauge response. It's non-toxic, even safe for ingestion in moderation, unlike human drugs.

Genetic and Species Notes

Sensitivity is hereditary—lions, tigers, and bobcats react too, but domestic cats vary widely. If your cat's unresponsive, silver vine or valerian offer similar kicks for non-responders.

TL;DR : Yes, catnip delivers a short, safe high via natural opioids—euphoria without the crash. Fun treat, not a staple.

Information gathered from public forums or data available on the internet and portrayed here.