tRNA does not have codons; it has anticodons that base‑pair with codons found on mRNA during translation.

What tRNA Actually Has

  • Each tRNA molecule carries a three‑base sequence called an anticodon.
  • This anticodon is complementary and antiparallel to a specific three‑base codon on mRNA.

Codons vs Anticodons

  • Codons are triplets on mRNA that specify amino acids or stop signals in the genetic code.
  • Anticodons are triplets on tRNA that recognize and bind those codons to bring in the correct amino acid.

How They Work Together

  • During translation, the tRNA anticodon temporarily pairs with its matching mRNA codon inside the ribosome, ensuring the right amino acid is added to the growing polypeptide chain.
  • This codon–anticodon pairing is a key part of maintaining accuracy (fidelity) in protein synthesis.

TL;DR: tRNA has anticodons , mRNA has codons ; they pair with each other so the correct amino acid gets added in the right order.

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