In the Netflix thriller His & Hers, Anna and Jack’s baby, Charlotte Alice Harper, dies suddenly while being looked after by Anna’s mother, Alice. The show explains that her death is described as “crib death,” an older term for Sudden Infant Death Syndrome (SIDS), meaning the baby’s passing is unexpected and without a clear medical explanation, typically occurring during sleep.

Within the story, this loss happens before the main timeline of the series and becomes the central trauma that breaks Anna and Jack’s marriage and shapes their behavior throughout the investigation. The series does not depict a violent act against the baby; instead, it frames the tragedy as an unexplained, sudden infant death while in the care of Anna’s mother.