Indianapolis is roughly 180–205 miles (about 290–330 km) from Chicago, depending on the exact route and starting/ending points. By car, that usually works out to about a 3.5–4.5 hour drive in normal traffic, mainly along I‑65.

If you fly between Indianapolis International Airport (IND) and Chicago O’Hare (ORD), the distance is about 175–285 km (around 175 miles), and the flight time is under an hour of airtime, though airport procedures add extra time.