To beat Mewtwo , you need to exploit its Psychic‑type weakness and either stall it out or hit it hard with Dark/Bug/Ghost moves , depending on the game.

Core strategy (most Pokémon games)

Mewtwo is a Psychic‑type with huge Special Attack, so the safest approach is:

  • Use Dark‑, Bug‑, or Ghost‑type moves (they super‑effect Mewtwo).
  • Avoid sending in pure Psychic or Fighting types that Mewtwo can OHKO.
  • If your team is underleveled, stall with Toxic + healing (e.g., Chansey‑style setups) until Mewtwo faints from poison damage.

Example “easy” team setups

1. Toxic‑stall (Let’s Go / older‑style games)

  • Lead with a high‑HP Pokémon (like Chansey or similar) that knows Toxic.
  • Let Mewtwo hit you once, then hit it with Toxic.
  • On following turns, spam healing (Soft‑Boil, Rest, etc.) while Mewtwo’s HP drains from poison.

2. Hard‑hitter (any main‑series game)

  • Use a Dark‑type with a strong physical move, such as Mega‑Gyarados with Crunch ; it’s immune to Psychic and hits Mewtwo for super‑effective damage.
  • Or run a Bug‑type like Scyther/Scizor with Swords Dance → X‑Scissor to burst Mewtwo down before it can set up.

3. Special‑tank option

  • A bulky Normal‑type like Snorlax can tank Psychic hits thanks to high Special Defense, then retaliate with Body Slam or other strong moves.

Quick matchup table (by role)

Role| Example Pokémon / move| Why it works
---|---|---
Toxic stall| Chansey + Toxic| Mewtwo dies slowly from poison while you heal. 19
Dark counter| Mega‑Gyarados + Crunch| Immune to Psychic, Dark moves are super effective. 1
Bug nuke| Scyther + Swords Dance + X‑Scissor| Fast setup and hard Bug‑type hits on Psychic. 3
Special tank| Snorlax| High Special Defense lets it live Psychic hits. 3

Extra tips

  • Save before the battle and soft‑reset if Mewtwo lands a bad crit or status.
  • If the game lets you, raise your Pokémon’s level a bit (or use candies/battle items) so your counters can survive at least one Psychic.

If you tell me which game you’re playing (e.g., Pokémon GO , Let’s Go , Scarlet/Violet Tera Raid , etc.), I can give a frame‑by‑frame plan tailored to that version.

Information gathered from public forums or data available on the internet and portrayed here.