in a wild-type e coli cell, which of the following genes is constitutively expressed?
In a wild-type E. coli cell, housekeeping genes (such as those encoding RNA polymerase core subunits, ribosomal RNAs, ribosomal proteins, and enzymes of central metabolism like glycolysis) are constitutively expressed.
Key idea
- Constitutive expression means the gene is transcribed at a relatively constant level, independent of specific environmental inducers or repressors.
- In wild-type E. coli , this applies mainly to essential āhousekeepingā functions , not to typical inducible operons like lac or trp , which are tightly regulated by nutrients (lactose, tryptophan, etc.).
Common exam-style options
When this question appears in genetics or microbiology exams, the constitutively expressed choice is usually something like:
- A gene encoding RNA polymerase subunit (e.g., rpoB/rpoC)
- A ribosomal RNA gene (rRNA, e.g., rrn operons)
- A core ribosomal protein gene
- A central metabolism enzyme (e.g., glycolytic enzyme)
Whereas genes like lacZ , trpE , or other catabolic/biosynthetic operon genes are not constitutive in a wild-type strain; they are induced or repressed depending on substrate or amino acid availability.
How to pick the answer
- If the options include a clear housekeeping gene (e.g., ārRNA geneā, āRNA polymerase geneā, āgene for a ribosomal proteinā) alongside regulatory/inducible genes (lac , trp , stress-response), choose the housekeeping gene as the constitutively expressed one.
TL;DR: In a wild-type E. coli , the constitutively expressed gene among typical choices is the one coding for a basic housekeeping function (rRNA, ribosomal protein, or RNA polymerase), not lac or trp operon genes.
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