In The Elder Scrolls IV: Oblivion (including Remastered), Nightshade is most easily found in a few reliable spots and shops.

Fast, easy sources

Buy Nightshade in the Imperial City

  • Go to the Imperial City Market District.
  • Enter The Main Ingredient and talk to Ogier Georick.
  • He usually sells 4–5 Nightshade at a time for a small amount of gold.
  • You can wait 3 in‑game days to refresh his stock.

Other alchemy shops that can stock Nightshade:

  • The Gilded Carafe – also in the Market District.
  • All Things Alchemical – in Skingrad.

Good world locations (plants in the wild)

Nightshade grows as small purple plants in certain regions; once picked, they respawn every 3 in‑game days , so you can farm them.

Particularly good areas:

  • West of Skingrad / West Weald region
    • Follow the road west of Skingrad; there are many Nightshade plants along the roadside and in nearby wilderness.
* Specific exterior “cells” with lots of plants include coordinates **(−2, −2)** which has around **18 plants** , plus others like **(1, −4)** and **(−1, −3)**.

* Near **Fat Ramp Camp** southwest of Skingrad you can find roughly **8 plants** you can harvest.
  • Southern Cyrodiil river area
    • Along the southern part of the map, following the river between Skingrad/Kvatch down toward Bravil , Nightshade can appear in clusters near the banks and surrounding wilderness.

Because plants regrow, you can make a little loop:

  1. Buy out The Main Ingredient in the Imperial City.
  1. Ride out west from Skingrad, sweep the West Weald and Fat Ramp Camp area.
  1. Optionally run a southern river circuit toward Bravil for extra plants.
  1. Wait 3 in‑game days, then repeat.

Why Nightshade matters

  • It is an alchemy ingredient with effects like Damage Health, Burden, Damage Luck, and Fortify Magicka , useful for offensive or utility potions.
  • It is also commonly needed in quests (notably cure‑related and alchemy tasks), which is why guides and quick videos highlight the Imperial City shop plus Skingrad region as go‑to spots.

Information gathered from public forums or data available on the internet and portrayed here.