For a generic “prelude” crossword clue, the most common answers are short synonyms that mean “introduction” or “opening.” Typical fills include:

  • INTRO (5 letters)
  • PROEM (5 letters)
  • LEADIN (6 letters)
  • OVERTURE (8 letters)

Which one is correct for your puzzle depends on:

  • The number of letters in the answer.
  • Any letters you already have from crossing clues.
  • Whether the clue is strictly musical (often “OVERTURE”) or more general (“INTRO,” “PROEM,” or “LEADIN”).

If you tell me the letter count and any known letters (like “_ N T R O”), I can help you narrow it to the exact answer.

Information gathered from public forums or data available on the internet and portrayed here.