The innermost layer of the uterus is called the endometrium.

Quick Scoop

  • The endometrium is the thin, soft lining that covers the inside of the uterine cavity.
  • It thickens each menstrual cycle to prepare for possible pregnancy and is shed during menstruation if fertilization does not occur.
  • The other main layers of the uterus are the myometrium (middle muscular layer) and the perimetrium/serosa (outer protective layer). Endometrium is specifically the innermost one.

So, for the fill‑in‑the‑blank style question
“The innermost layer of the uterus is called the ______,”
the correct answer is: endometrium.

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