Schedule 3 drugs (often written as “Schedule III”) are controlled substances that have accepted medical uses but a moderate potential for abuse and dependence, lower than Schedule I or II but higher than Schedule IV or V. They are tightly regulated and usually require a prescription, and misuse can still lead to legal trouble and health risks.

What “Schedule 3” Means

  • Moderate abuse risk : These drugs can cause psychological or physical dependence, but the risk is considered lower than with Schedule II drugs like oxycodone or fentanyl.
  • Accepted medical use : Schedule 3 drugs are legal to prescribe and use for specific medical conditions, such as pain management, hormone therapy, or anesthesia.
  • Regulated access : Possession without a valid prescription, or distribution outside medical channels, can lead to criminal charges and penalties that vary by state and country.

Common Types of Schedule 3 Drugs

  • Certain opioid combinations : Products that contain small amounts of opioids combined with non-opioid ingredients, such as some codeine combinations for pain or cough.
  • Anabolic steroids : Hormone-like substances used medically for certain deficiencies but often misused for bodybuilding and performance enhancement.
  • Dissociative anesthetics : Drugs used in anesthesia and sometimes in veterinary medicine, such as ketamine and certain ketamine-like combinations.
  • Other CNS depressants and stimulants : Some barbiturate derivatives and weight-loss stimulants that have a moderate risk of dependence.

Examples of Schedule 3 Drugs

Here are some widely cited examples (names may vary by country and brand):

  • Opioid combinations
    • Tylenol with codeine (acetaminophen with less than 90 mg codeine per dosage unit, sometimes called “Tylenol 3”).
* Certain cough syrups or tablets that combine codeine with other non-narcotic ingredients.
  • Anabolic steroids and related hormones
    • Testosterone preparations used for hormone replacement therapy.
* Other anabolic steroids classified as Schedule 3 under U.S. federal law.
  • Dissociative and other anesthetics
    • Ketamine, used in human and veterinary anesthesia and increasingly in specialized clinical settings.
* Tiletamine with zolazepam, a combination used mainly in veterinary practice.
  • Miscellaneous Schedule 3 substances
    • Buprenorphine (e.g., some formulations used in medication-assisted treatment for opioid use disorder).
* Nalorphine, an older opioid agonist–antagonist with limited modern use.

Legal and Safety Notes

  • Never use these medications without a prescription, and never change your dose or share them with others; doing so can be both unsafe and illegal.
  • Laws and specific classifications can differ by country and sometimes by state, so the exact list of Schedule 3 drugs where you live may not match U.S. federal classifications.
  • If there are concerns about misuse, dependence, or withdrawal from any Schedule 3 drug, medical and addiction specialists can provide confidential assessment and treatment options.

Information gathered from public forums or data available on the internet and portrayed here.