Urinary tract infections (UTIs) in dogs usually start when bacteria get into the urinary tract and are able to multiply in the bladder or beyond.

Main causes of UTI in dogs

  • Bacteria entering through the urethra
    The most common cause is bacteria (often E. coli from the skin or fecal area) traveling up the urethra into the bladder, where they trigger infection and inflammation.

Female dogs are at higher risk because their urethra is shorter and wider, giving bacteria easier access to the bladder.

  • Weakened immune system or other illnesses
    Dogs with a weakened immune system from illness, poor nutrition, or chronic disease are less able to clear invading bacteria, so infections take hold more easily.

Conditions like diabetes (sugar in the urine feeding bacteria), chronic kidney disease, and hormone-related problems can all predispose a dog to recurrent UTIs.

  • Anatomical issues and incontinence
    Extra or ā€œfoldedā€ vulvar skin in some females can trap moisture and bacteria near the urethra, letting them travel upward into the bladder.

Dogs with urinary incontinence (for example, urethral sphincter mechanism incompetence in older females) may leak small amounts of urine, which encourages bacterial growth and backflow into the bladder.

  • Stones, crystals, or obstruction
    Bladder stones or crystals can irritate the bladder lining, damage its natural defenses, and create surfaces where bacteria can stick and multiply.

Anything that partially blocks urine flow (stones, tumors, severe inflammation) means urine sits longer in the bladder, giving bacteria more time to grow.

  • Tumors and bladder/prostate disease
    Cancer or other tumors in the urinary tract, as well as chronic bladder inflammation, make the environment inside the bladder more vulnerable to infection.

In male dogs, prostate infections or enlargement can both be a cause of UTIs and a consequence of them, often requiring longer antibiotic treatment.

  • Spinal or neurologic problems and trauma
    Dogs with spinal cord disease or other neurologic issues may not empty their bladder fully, or may lose normal control of urination, which allows bacteria to persist in stagnant urine.

Trauma or stress to the urinary tract can also inflame tissues and lower local defenses, making bacterial infection more likely.

Quick note on ā€œsimpleā€ vs. complicated UTIs

  • A ā€œsimpleā€ UTI is usually a one-off infection in an otherwise healthy dog, most often from ascending bacteria like E. coli.
  • Recurrent or complicated UTIs usually have an underlying cause—stones, anatomical problems, chronic disease, or tumors—that must be identified and treated to stop the cycle.

If your dog is peeing frequently, straining, having accidents, or you see blood in the urine, contact a vet promptly—UTIs are painful and can spread to the kidneys if not treated.