Multiple pharmaceutical companies make leucovorin (also called leucovorin calcium or folinic acid), including both brand‑name and generic manufacturers in different countries.

Key manufacturers and brands

  • GSK (GlaxoSmithKline) markets a branded leucovorin product called Wellcovorin in the US and is involved in FDA label updates for this medicine.
  • Teva Pharmaceuticals manufactures generic Leucovorin Calcium Tablets, USP in the US as an alternative to Wellcovorin.
  • In Canada, several companies market leucovorin products, including JAMP Pharma (JAMP Leucovorin) and Mint Pharmaceuticals (MINT‑LEUCOVORIN).

API and bulk manufacturers

Beyond finished drug products, many companies manufacture leucovorin as an active pharmaceutical ingredient (API) or bulk material, which is then used by others to make final tablets or injections. Examples listed in industry directories include:

  • Rochem International Inc
  • ALP Pharm
  • Cerbios‑Pharma SA
  • Global Calcium
  • Merck & Cie
  • Spectrum Chemical
  • Willow Birch Pharma

These lists show that leucovorin is not made by a single company; instead, it is produced by many manufacturers worldwide, with local availability depending on country and regulatory approvals.