“A través de las colinas de Sonora ” means “through the hills of Sonora” or “across the hills of Sonora” in English. The phrase uses a través de to mean “through” or “across,” and las colinas means “the hills.”

If you want the most natural translation in a sentence, “through the hills of Sonora” is usually the best fit. “Sonora” is left as a place name rather than translated.