Uracil pairs with adenine in RNA, forming a standard A–U base pair held together by two hydrogen bonds.

Quick Scoop: What Does Uracil Pair With?

In RNA, uracil (U) is one of the four main nitrogenous bases and takes the place that thymine (T) has in DNA. The key rule is that adenine (A) pairs specifically with uracil (U), just like adenine pairs with thymine in DNA.

  • Uracil (U) is a pyrimidine base found primarily in RNA.
  • In standard base pairing, uracil pairs with adenine (A) to form an A–U pair.
  • This A–U pair is stabilized by two hydrogen bonds, similar to the A–T pair in DNA.

So if you’re visualizing an RNA strand, whenever you see an A on one strand, the complementary base on the other strand is U, not T.

Tiny TL;DR

Uracil pairs with adenine in RNA, forming an A–U base pair connected by two hydrogen bonds.

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