Luffy defeats Donquixote Doflamingo in episode 733 of the One Piece anime, titled “Luffy, the Man Who Will Become the Pirate King.”

Quick Scoop: The Exact Episode

  • The decisive finishing blow (King Kong Gun) that ends the fight happens in Episode 733.
  • The broader Luffy vs. Doflamingo battle stretches roughly from episodes 721–733 , covering the build‑up, Gear 4 reveal, and the final clash in Dressrosa.

So if you just want to see Luffy finally put Doflamingo down, jump straight to Episode 733.

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