Most bug bites feel better with a cold compress, an anti-itch cream like 1% hydrocortisone, and an oral antihistamine such as cetirizine or loratadine. Try not to scratch, because that raises the risk of irritation and infection.

What helps most

  • Apply a cold, damp cloth or ice wrapped in cloth for 10 to 20 minutes.
  • Use calamine lotion or 0.5% to 1% hydrocortisone cream on the itchy area.
  • Consider an over-the-counter antihistamine for stubborn itching.
  • Take ibuprofen or acetaminophen if the bite is painful.

Simple home care

  • Wash the bite gently with soap and water.
  • Raise the area if it is on an arm or leg to help with swelling.
  • A baking soda paste or oatmeal can also soothe some bites.
  • Avoid scratching or popping any blister that forms.

Get medical help

Seek urgent care right away if you have trouble breathing, swelling of the lips, face, tongue, or throat, dizziness, or a widespread rash.

See a clinician if redness, warmth, swelling, pus, fever, or body aches develop, since that can mean infection or another problem.

If you want, I can turn this into a very short first-aid checklist.