The Major League Baseball regular season typically starts in late March or early April each year, with an official “Opening Day” that marks the beginning of the 162-game schedule.

2026 MLB regular season start

  • In 2026, MLB’s regular season is scheduled to begin with Opening Day matchups on Wednesday, March 25, 2026.
  • That date is when the full slate of regular-season games starts and is treated as the start of the MLB regular season.

General rule of thumb

  • Most seasons: MLB regular season runs late March/early April through late September or early October.
  • Some years include special early international series (like Tokyo), but the main answer to “when does baseball regular season start” is “late March or early April,” with the exact date set year by year.

Information gathered from public forums or data available on the internet and portrayed here.