Opening Day for the Detroit Tigers’ 2026 season is Thursday, March 26, 2026, on the road against the San Diego Padres.

At Comerica Park in Detroit, the Tigers’ home opener—often what fans locally call “Opening Day” or “Detroit’s Biggest Party”—is scheduled for Friday, April 3, 2026, against the St. Louis Cardinals.

So in short: season Opening Day is March 26 (at Padres), and Detroit’s home Opening Day at Comerica Park is April 3 vs. the Cardinals.