Each main Fallout game is set in a different region of a post‑nuclear United States, usually a warped version of a real city or state.

Mainline Fallout games and where they take place

Fallout (1997)

  • Core setting: Southern California wasteland.
  • Key areas: The Hub, Junktown, Shady Sands, and the remnants of the Necropolis and the Boneyard (ruined Los Angeles).
  • Vibe: Desert communities, early post‑war civilization trying to rebuild around old pre‑war ruins.

Fallout 2 (1998)

  • Core setting: Northern California and parts of Nevada.
  • Key areas: Arroyo, New Reno (twisted “Vegas‑lite”), Vault City, San Francisco, and oil rig out in the Pacific.
  • Vibe: More developed wasteland with crime‑ridden cities, weird high‑tech pockets, and a stronger “wild West plus Mad Max” feel.

Fallout 3 (2008)

  • Core setting: The Capital Wasteland, around Washington, D.C.
  • Key areas: The National Mall, the Washington Monument, Rivet City, Megaton, and Vault 101.
  • Vibe: Iconic U.S. landmarks half‑buried in rubble, heavy ruin‑exploration around government buildings and monuments.

Fallout: New Vegas (2010)

  • Core setting: Mojave Wasteland – around Las Vegas, Nevada, stretching into bits of California and Arizona.
  • Key areas: New Vegas Strip, Hoover Dam, the NCR‑controlled Mojave Outpost, and Caesar’s Legion territory along the Colorado River.
  • Vibe: Faded casino glitz surrounded by desert, with rival factions trying to control Hoover Dam and the Strip.

Fallout 4 (2015)

  • Core setting: The Commonwealth – greater Boston and surrounding Massachusetts.
  • Key areas: Ruined Boston proper (Back Bay, Boston Common), Diamond City (built in Fenway Park), the Glowing Sea in the southwest, and outlying settlements across the Commonwealth.
  • Vibe: Dense city exploration mixed with small New England towns, lots of vertical ruins and old American history twisted by radiation.

Fallout 76 (2018, always‑online)

  • Core setting: Appalachia – West Virginia.
  • Key areas: Versions of real‑world spots like the Greenbrier resort, Mothman Museum, Camden Park, and the state’s mountainous regions.
  • Vibe: Earlier in the timeline (Reclamation Day), more wilderness and small communities, heavy “backwoods Americana” energy.

Spin‑offs and tactical titles

Fallout Tactics: Brotherhood of Steel (2001)

  • Core setting: The Midwest, primarily around Illinois and up through the central United States.
  • Vibe: Squad‑based military campaign following the Brotherhood of Steel’s expansion into middle‑America towns, farms, and industrial zones.

Fallout: Brotherhood of Steel (2004, console spin‑off)

  • Core setting: Texas (largely central and western parts, in a non‑canonical, looser interpretation of the series).
  • Vibe: Linear action‑RPG through dusty Texas towns and bunkers under Brotherhood control.

Popular DLC settings (quick hits)

Even though your question is about “each Fallout game,” most fans also talk about the big DLC areas because they feel like mini‑games of their own:

  • Fallout 3
    • Operation: Anchorage – Simulated liberation of Anchorage, Alaska.
    • The Pitt – Ruined Pittsburgh, Pennsylvania.
    • Point Lookout – Swampy coastal Maryland.
    • Mothership Zeta – Alien spacecraft in orbit.
  • Fallout: New Vegas
    • Dead Money – Sierra Madre Casino in the mountains.
    • Honest Hearts – Zion National Park, Utah.
    • Old World Blues – Big MT research crater.
    • Lonesome Road – The Divide, a devastated canyon region.
  • Fallout 4
    • Far Harbor – A fog‑choked island off the coast of Maine.
    • Nuka‑World – A massive Nuka‑Cola theme park somewhere outside the Commonwealth.

Quick HTML table overview

Below is an HTML table since you requested tables as HTML:

html

<table>
  <thead>
    <tr>
      <th>Game</th>
      <th>Primary Setting</th>
      <th>Real‑World Region</th>
      <th>Notes</th>
    </tr>
  </thead>
  <tbody>
    <tr>
      <td>Fallout</td>
      <td>Southern California wasteland</td>
      <td>SoCal (incl. Los Angeles area)</td>
      <td>Classic desert towns, The Hub, Shady Sands.</td>
    </tr>
    <tr>
      <td>Fallout 2</td>
      <td>Post‑war Northern California & Nevada</td>
      <td>NorCal coast, “New Reno”, Pacific oil rig</td>
      <td>More advanced settlements and crime cities.</td>
    </tr>
    <tr>
      <td>Fallout 3</td>
      <td>Capital Wasteland</td>
      <td>Washington, D.C. and surroundings</td>
      <td>Ruined monuments, metro tunnels, Rivet City.</td>
    </tr>
    <tr>
      <td>Fallout: New Vegas</td>
      <td>Mojave Wasteland</td>
      <td>Las Vegas, Hoover Dam, Mojave Desert</td>
      <td>New Vegas Strip & competing factions.</td>
    </tr>
    <tr>
      <td>Fallout 4</td>
      <td>The Commonwealth</td>
      <td>Boston & Massachusetts</td>
      <td>Diamond City, Glowing Sea, dense urban ruins.</td>
    </tr>
    <tr>
      <td>Fallout 76</td>
      <td>Appalachia</td>
      <td>West Virginia</td>
      <td>Earlier in timeline, more wilderness and folklore.</td>
    </tr>
    <tr>
      <td>Fallout Tactics</td>
      <td>Midwestern wasteland</td>
      <td>Illinois and central U.S.</td>
      <td>Brotherhood campaign through the Midwest.</td>
    </tr>
    <tr>
      <td>Brotherhood of Steel (2004)</td>
      <td>Texas wasteland</td>
      <td>Central/west Texas</td>
      <td>Action‑RPG console spin‑off, loosely canonical.</td>
    </tr>
  </tbody>
</table>

TL;DR: Every Fallout game stakes out its own slice of ruined America—from SoCal and NorCal, to D.C., Vegas, Boston, and West Virginia—plus side trips to Alaska, Utah’s Zion, off‑shore islands, and even orbit. Information gathered from public forums or data available on the internet and portrayed here.