The basic chords to play “Where Is My Mind?” by Pixies on guitar are:

  • Verse/chorus main progression (key of E major):
    E – C#m – G# – A

Played in a simple 4-chord loop, it looks like this, one chord per bar:

  • E | C#m | G# | A | (repeat)

For the “Way out in the water, see it swimmin’” line, many chord sheets add this tag:

  • E – G# – A – Am – C#m – B

So a very common, easy structure is:

  • Verses: E – C#m – G# – A (loop)
  • “Where is my mind?” hook: same loop (E – C#m – G# – A)
  • “Way out in the water…” tag: E – G# – A – Am – C#m – B

If you want to strum along in a simple way, you can just use downstrokes on each beat with that 4-chord loop and you’ll already be very close to the original feel.