which of the following best describes how high levels of cholesterol affect the cell membrane at certain temperatures?
High levels of cholesterol make the cell membrane less fluid at high temperatures and more fluid at low temperatures by buffering how much fluidity changes with temperature.
Core idea
- At high temperatures, cholesterol stabilizes and stiffens the membrane, preventing it from becoming too fluid or āmelting.ā
- At low temperatures, cholesterol disrupts tight packing of phospholipid tails, preventing the membrane from becoming too rigid or freezing.
- Overall, cholesterol reduces the temperatureādependence of membrane fluidity: it acts as a fluidity ābufferā so the membrane stays in a useful, semiāfluid state across a wider temperature range.
So, among typical answer choices, the best description is usually:
āCholesterol decreases membrane fluidity at high temperatures and increases membrane fluidity at low temperatures, helping maintain relatively constant fluidity over a range of temperatures.ā