The FDA is headed by the Commissioner of Food and Drugs , and the FDA’s official page says that role is held by Dr. Martin A. Makary.

What that means

The FDA is part of the U.S. Department of Health and Human Services, and the commissioner is the top official responsible for leading the agency. The FDA page also identifies Dr. Makary as the 27th commissioner and says he was sworn in on January 3, 2025.

In practice

If you’re asking who makes the final calls at the agency, it’s the commissioner at the top, though major FDA decisions still flow through the agency’s offices and review divisions. There has also been recent public discussion about leadership and possible changes at the FDA, but the current official head listed by the FDA is still Dr. Makary.

Quick line

So, the short answer is: Dr. Martin A. Makary is in charge of the FDA.