The most common answer is Karthus — he’s widely treated as one of the highest-damage junglers because his kit can deal huge sustained and global damage, especially in late game. If you mean burst/one-shot damage , then Kha’Zix , Rengar , or Master Yi are often the scarier picks depending on patch, build, and enemy comp.

Quick Scoop

For pure damage over a game, Karthus is the safest single-name answer from the sources I found. For explosive kill pressure, Kha’Zix and Rengar are the usual “high damage jungler” names people bring up in discussion. Master Yi also shows up often because a fed Yi can melt teams once he gets rolling.

Why Karthus stands out

Karthus does damage in a way most junglers can’t match: his ultimate hits everywhere, and he keeps contributing even after dying. That makes him especially strong in long fights and late-game teamfights. In other words, if the question is “who usually tops damage charts from the jungle role,” Karthus is the best fit.

Other high-damage options

  • Kha’Zix: huge isolated burst and strong assassination threat.
  • Rengar: fast damage output and brutal snowball potential.
  • Master Yi: terrifying sustained damage when ahead.
  • Viego: strong damage plus reset pressure in fights.
  • Gwen: more niche jungle pick, but can still output massive AP damage.

Best one-line answer

If you want the highest damaged jungler overall , say Karthus. If you want the most explosive damage jungler , say Kha’Zix or Rengar depending on whether you want assassin burst or snowball melee kill pressure.

TL;DR

Karthus is the best all-around answer for highest damage jungle output, while Kha’Zix and Rengar are the big burst-damage alternatives.