George Kittle is out because of a sprained ankle he suffered in the 49ers’ Week 16 game against the Indianapolis Colts, and the team has ruled him inactive for the Week 17 matchup vs. the Chicago Bears.

Quick Scoop

  • George Kittle left the Week 16 win over the Colts with an ankle injury in the third quarter and did not return.
  • Further tests showed a sprained ankle, and he was held out of practice all week leading up to Week 17.
  • For the Sunday night game against the Bears, the 49ers listed him as inactive, confirming he would not play.

Why he’s specifically out

  • The team is being cautious because it’s a low‑ to mid‑grade ankle sprain and they want to avoid making it worse before the postseason push.
  • He had already missed multiple games earlier this season with a hamstring issue, so medical staff are managing his overall workload carefully.

What it means tonight

  • With Kittle sidelined, Jake Tonges and the rest of the tight end group are expected to absorb most of his snaps and targets in the offense.
  • The 49ers’ passing game may lean more on wide receivers and Christian McCaffrey in key third‑down and red‑zone situations.

Fantasy / fan angle

  • For fantasy managers, Kittle is a must‑sit for this week, and any late‑swap options from the Sunday night or Monday game become crucial.
  • Fans should watch for updates in the coming days, but for now he is ruled out for the Bears game and considered week‑to‑week with the ankle sprain.

Information gathered from public forums or data available on the internet and portrayed here.