During mitosis, the mitotic spindle begins to form during prophase.

Quick Scoop

  • The mitotic spindle starts assembling in late prophase , as centrosomes move to opposite poles and microtubules grow between them.
  • By metaphase , the spindle is fully formed and attached to chromosomes aligned at the cell’s equator.
  • In simple textbook terms, if you are asked “During what phase does the spindle form?”, the expected answer is prophase.

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