Pfizer likely made tens of billions from its COVID vaccine, depending on whether you mean revenue or profit. A widely cited estimate says Pfizer generated about $35 billion in net profits from its COVID-related products in 2021 and 2022 combined, while Pfizer’s own 2022 annual report shows $37.8 billion in Comirnaty-related revenue for that year alone.

What the numbers mean

  • Revenue is the money Pfizer brought in from vaccine sales.
  • Profit is what was left after costs.
  • So when people ask “how much did Pfizer profit,” the answer is usually closer to the net profit figure, not revenue.

Useful context

Pfizer’s COVID vaccine was an enormous business during the pandemic peak, but sales have fallen sharply since then as demand declined. Even so, the vaccine remained a major earnings driver for a while after the initial rollout.

Simple takeaway

If you want the short version: around $35 billion in net profits from COVID- related products in 2021–2022 , with $37.8 billion in Comirnaty-related revenue in 2022.