Prokaryotic cells, such as bacteria and archaea, are the type of cells that do not have a nucleus.

Quick Scoop

  • Prokaryotic cells lack a membrane-bound nucleus; their DNA sits in an open region called the nucleoid instead.
  • In contrast, eukaryotic cells (like plant and animal cells) do have a true nucleus enclosed by a nuclear membrane.
  • A well-known example of anucleated (no-nucleus) cells in humans is mature red blood cells, which lose their nucleus during development, but these are a special case within an otherwise eukaryotic organism.

TL;DR: When you see the question “which type of cell does not have a nucleus?”, the standard answer is: prokaryotic cells (like bacteria).

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