Leucovorin (folinic acid) is an old, off‑patent drug, so it is now made by multiple generic manufacturers rather than a single company.

Key point

  • In the United States, leucovorin is available only as a generic drug; the original brand, Wellcovorin, was once marketed by GSK but they no longer manufacture or sell it.
  • GSK still holds the New Drug Application (NDA) for Wellcovorin, mainly for regulatory and label‑update purposes, but the actual marketed products are produced by generic companies.

Examples of manufacturers

Different dosage forms (tablets, injections) are made by various generic firms; examples include:

  • Teva (leucovorin calcium tablets, USP, a generic equivalent to Wellcovorin tablets).
  • Hikma (leucovorin calcium injection; they received FDA approval to supply this to the U.S. market).
  • Additional generics exist in North America and globally (for example, Canadian monographs list JAMP Leucovorin and other branded generics), but these are all versions of the same active ingredient produced by different manufacturers.

How to find the exact maker of your product

  • Check the drug label or packaging: the manufacturer’s or distributor’s name is usually printed near the bottom of the front or back panel.
  • For prescriptions in the U.S., your pharmacy label often lists the manufacturer in small text, or you can ask the pharmacist which company’s leucovorin they dispense.
  • National drug databases (such as FDA’s online drug listings or Health Canada’s Drug Product Database) allow you to search “leucovorin” and see all currently registered manufacturers and products in your country.

Information gathered from public forums or data available on the internet and portrayed here.